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In this unit the finer points of
molecular biology are explored. The emphasis is on biotechnology,
the molecular genetics of viruses and bacteria, and gene regulation
in eukaryotes.
Lecture
Chapter 18 Lecture 1: Genetics of Viruses (print) (audio 21:00)
Chapter 18 Lecture 2: Prions (print) (audio 21:00)
Chapter 18 Lecture 3: Genetics of Bacteria (print) (audio 15:44)
Chapter 18 Lecture 4: The Operon: How Gene Expression is Regulated (print) (audio 26:45)
Chapter 18 Lecture 5: Strange and Unexpected Biology (print) (audio 25:30)
Chapter 19 Lecture 1: Eukaryotic DNA Packaging (print)
Chapter 19 Lecture 2: "Junk" DNA (print) (audio 26:12)
Chapter 19 Lecture 3: Eukaryotic Gene Expression (print) (audio 4:33)
Chapter 20 Lecture 1: DNA Technology: Tools of the Trade- Restriction Enzymes & Gel Electrophoresis (print) (audio 19:47)
Chapter 20 Lecture 2: Eukaryotic Gene Expression and PCR (print) (audio 31:59)
PCR Animation (From the DNA Learning Center)
PCR Animation (from Roche Labs)
PCR Song Parody (lyrics) ("We Are The World" original video)
Homework
Chapter 18 Free Response Questions
Chapter 19 & 20 Free Response Questions
Tiny Specks of Misery, Both Vile and Useful
Nature's Bioterrorist (pdf)
Craig Venter Interview in Seed Magazine (December 2008)
Craig Venter's Fantastic Voyage (Wired Magazine August 2004) (print version)
The Genome Warrior (The New Yorker Article on Craig Venter, June 2000)
A Life Decoded: My Genome- My Life By Craig Venter
Scientist Creates Life- Almost (Time Magazine, January 2008)
Artificial Life? Old News (Wired Magazine, January 2008)
Bacteria vs. Humans: Which is the Best Species? ( E.O. Wilson in the New York Times)
How To Live Forever (The Economist- January 2008)
DNAi Genome Website
Alu and Early Human Populations (pdf)
One Genome, Many Types of Cells (pdf)
Lab
Bioinformatics Lab (Simulation)
Test Prep
Chapter 18 Test Hints
Chapters 19 & 20 Test Hints
Web Resources
Flu Attack! How A Virus Invades Your Body (Animation)
Complete Genomics
23andMe
Navigenics
Decode Genetics
Bioinformatics
Microarrays
Human Immunodeficiency Virus (HIV) Animation
Nextgencode (Michael Crichton's fake biotech website for his book "Next")
The Broad Institute
Nova: Ghost in Your Genes
23andMe article
The Lac Operon Animation (Excellent!)
Introduction to Genetic Analysis (Excellent Resource!)
Human Mitochondrial DNA Wheel
Fun
PCR Song (lyrics)
BioRad Songs
Readings
DNA Barcodes (Wall Street Journal, December 2009) Graphic 1 Graphic 2
Redefining the Gene (Seed Magazine, January 2008)
Are Cloned Pets The Real Thing? (NY Times 12/31/08)
Coriell Institute for Medical Research
Time Magazine: Invention of the Year 2008
Patient’s DNA May Be Signal to Tailor Medication (NY Times 12/29/08)
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